Brief Information of the Compound and Protein
Compound Name
4-Phenethylamino-6,7,8,9-tetrahydro-pyrimido[4,5-b]indolizine-10-carbonitrile
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PubChem ID
CID: 11359019
SID: 16451342
Canonical SMILES
N#Cc1c2CCCCn2c2c(NCCc3ccccc3)ncnc12
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Compound Formula C19H19N5
Compound Structure
Protein Name
Multidrug resistance-associated protein 1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
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ABCC subfamily
Uniprot ID
P33527
Gene Name
ABCC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR Homo sapiens (Human)  2
1
IC50 = 4980 nM
   TI
   LI
   LO
   TS
2
IC50 = 8370 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 >= 250 nM