Brief Information of the Compound and Protein
Compound Name
4-(3-phenylpropylamino)-6,7,8,9-tetrahydropyrimido[4,5-b]indolizine-10-carbonitrile
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PubChem ID
CID: 127049509
Canonical SMILES
N#Cc1c2CCCCn2c2c(NCCCc3ccccc3)ncnc12
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Compound Formula C20H21N5
Compound Structure
Protein Name
Multidrug resistance-associated protein 1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCC subfamily
Uniprot ID
P33527
Gene Name
ABCC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR Homo sapiens (Human)  5
1
GI50 = 450 nM
   TI
   LI
   LO
   TS
2
GI50 = 751 nM
   TI
   LI
   LO
   TS
3
GI50 = 2410 nM
   TI
   LI
   LO
   TS
4
IC50 = 2500 nM
   TI
   LI
   LO
   TS
5
IC50 = 2840 nM
   TI
   LI
   LO
   TS