Brief Information of the Compound and Protein
Compound Name
5-cyclopropyl-4-[4-(2-phenylethyl)piperazin-1-yl]pyrrolo[3,2-d]pyrimidine-7-carbonitrile
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PubChem ID
CID: 127051983
Canonical SMILES
N#Cc1cn(C2CC2)c2c(ncnc12)N1CCN(CCc2ccccc2)CC1
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Compound Formula C22H24N6
Compound Structure
Protein Name
Multidrug resistance-associated protein 1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCC subfamily
Uniprot ID
P33527
Gene Name
ABCC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR Homo sapiens (Human)  5
1
GI50 = 395 nM
   TI
   LI
   LO
   TS
2
GI50 = 588 nM
   TI
   LI
   LO
   TS
3
GI50 = 827 nM
   TI
   LI
   LO
   TS
4
IC50 = 200 nM
   TI
   LI
   LO
   TS
5
IC50 = 247 nM
   TI
   LI
   LO
   TS