Brief Information of the Compound and Protein
Compound Name
4-[4-(2-phenylethyl)piperazin-1-yl]-5-propan-2-ylpyrrolo[3,2-d]pyrimidine-7-carbonitrile
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PubChem ID
CID: 127051982
Canonical SMILES
CC(C)n1cc(C#N)c2ncnc(N3CCN(CCc4ccccc4)CC3)c12
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Compound Formula C22H26N6
Compound Structure
Protein Name
Multidrug resistance-associated protein 1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCC subfamily
Uniprot ID
P33527
Gene Name
ABCC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000348 H69AR Homo sapiens (Human)  2
1
IC50 = 821 nM
   TI
   LI
   LO
   TS
2
IC50 = 1240 nM
   TI
   LI
   LO
   TS