Brief Information of the Compound and Protein
Compound Name
(4S,6S)-4-(2,4-difluoro-5-pyrimidin-5-ylphenyl)-6-methyl-6-(5-methyl-1,2-oxazol-4-yl)-4,5-dihydro-1,3-thiazin-2-amine
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PubChem ID
CID: 118517247
Canonical SMILES
Cc1oncc1[C@]1(C)C[C@H](N=C(N)S1)c1cc(c(F)cc1F)-c1cncnc1
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Compound Formula C19H17F2N5OS
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000008 H4 Homo sapiens (Human)  1
1
IC50 = 180 nM
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