Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2,2-dimethylpropyl)-5-[5-(2-hydroxypropan-2-yl)-2-methylphenyl]-3-methylimidazo[4,5-b]pyridin-2-one
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 PubChem ID
CID: 54761054
SID: 131525168
Canonical SMILES
Cc1ccc(cc1-c1ccc2n(CC(C)(C)C)c(=O)n(C)c2n1)C(C)(C)O
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Compound Formula C22H29N3O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 61 nM
   TI
   LI
   LO
   TS
2
EC50 = 63 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 600 nM