Brief Information of the Compound and Protein
Compound Name
(3S)-1-[6-methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]pyridin-2-yl]pyrrolidin-3-ol
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PubChem ID
CID: 127047414
Canonical SMILES
Cc1nc(ccc1-c1cc(cc2[nH]ncc12)C(F)(F)F)N1CC[C@H](O)C1
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Compound Formula C18H17F3N4O
Compound Structure
Protein Name
Methionine aminopeptidase 2
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MG clan
>
Metallo protease M24A subfamily
Uniprot ID
P50579
Gene Name
METAP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
EC50 = 65 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS