Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[8-[4-[(2,4-dichlorophenyl)methylamino]pyrimidin-2-yl]-2,8-diazaspiro[4.5]decan-2-yl]-pyrrolidin-2-ylmethanone
    Show/Hide
 PubChem ID
CID: 127045975
Canonical SMILES
Clc1ccc(CNc2ccnc(n2)N2CCC3(CCN(C3)C(=O)C3CCCN3)CC2)c(Cl)c1
    Show/Hide
Compound Formula C24H30Cl2N6O
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51679
Gene Name
CCR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 25.12 nM
   TI
   LI
   LO
   TS