Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(2,4-dichlorophenyl)methyl]-2-[2-(pyrrolidin-2-ylmethyl)-2,8-diazaspiro[4.5]decan-8-yl]pyrimidin-4-amine
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 PubChem ID
CID: 127045756
Canonical SMILES
Clc1ccc(CNc2ccnc(n2)N2CCC3(CCN(CC4CCCN4)C3)CC2)c(Cl)c1
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Compound Formula C24H32Cl2N6
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51679
Gene Name
CCR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 7.943 nM
   TI
   LI
   LO
   TS
2
Ki = 1.585 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 199.53 nM