Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(2,4-dichlorophenyl)methyl]-2-[2-[[(2R)-pyrrolidin-2-yl]methyl]-2,8-diazaspiro[4.5]decan-8-yl]pyrimidin-4-amine
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 PubChem ID
CID: 127047612
Canonical SMILES
Clc1ccc(CNc2ccnc(n2)N2CCC3(CCN(C[C@H]4CCCN4)C3)CC2)c(Cl)c1
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Compound Formula C24H32Cl2N6
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51679
Gene Name
CCR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 5.012 nM
   TI
   LI
   LO
   TS
CL000059 HuT 78
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 6.31 nM
   TI
   LI
   LO
   TS