Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(10R)-3-propyl-10-(propylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
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 PubChem ID
CID: 127046255
Canonical SMILES
CCCN[C@@H]1Cc2cccc3n(CCC)c(=O)n(C1)c23
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Compound Formula C16H23N3O
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000153 CHOP
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 56.1 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1423 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 21.7 nM
   TI
   LI
   LO
   TS
2
Ki = 47.9 nM
   TI
   LI
   LO
   TS