Brief Information of the Compound and Protein
Compound Name
(10R)-10-(dipropylamino)-3-propyl-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
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PubChem ID
CID: 127047229
Canonical SMILES
CCCN(CCC)[C@@H]1Cc2cccc3n(CCC)c(=O)n(C1)c23
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Compound Formula C19H29N3O
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000153 CHOP Cricetulus griseus (Chinese hamster)  1
1
EC50 = 3.7 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 51.9 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 3.39 nM
   TI
   LI
   LO
   TS
2
Ki = 6.05 nM
   TI
   LI
   LO
   TS