Brief Information of the Compound and Protein
Compound Name
7-(1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl)-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]quinazolin-4-amine
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PubChem ID
CID: 127047969
Canonical SMILES
COc1cc(CCc2cc(Nc3ncnc4cc(ccc34)N3CCN4CCCCC4C3)n[nH]2)cc(OC)c1
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Compound Formula C29H35N7O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P21802
Gene Name
FGFR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000432 KATO III Homo sapiens (Human)  1
1
IC50 < 0.4 nM
   TI
   LI
   LO
   TS
CL000431 SNU-16 Homo sapiens (Human)  1
1
IC50 = 0.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.2 nM