Brief Information of the Compound and Protein
Compound Name
[3-[4-amino-5-[3-[(4-methyl-7-oxabicyclo[2.2.1]heptan-1-yl)methoxy]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]methanol
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Canonical SMILES
CC12CCC(COc3cccc(c3)-c3cn([C@@H]4C[C@H](CO)C4)c4ncnc(N)c34)(CC1)O2
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Compound Formula C25H30N4O3
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 183 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 47 nM