Brief Information of the Compound and Protein
Compound Name
5-[3-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl]-7-[3-[(1-oxo-1,4-thiazinan-4-yl)methyl]cyclobutyl]pyrrolo[2,3-d]pyrimidin-4-amine
    Show/Hide
Canonical SMILES
Nc1ncnc2n(cc(-c3cccc(OCC45CCC(CC4)O5)c3)c12)[C@@H]1C[C@H](CN2CC[S+]([O-])CC2)C1
    Show/Hide
Compound Formula C28H35N5O3S
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 64 nM
   TI
   LI
   LO
   TS