Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[2-fluoro-5-(oxetan-2-ylmethoxy)phenyl]-7-[3-[(1-oxo-1,4-thiazinan-4-yl)methyl]cyclobutyl]pyrrolo[2,3-d]pyrimidin-4-amine
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Canonical SMILES
Nc1ncnc2n(cc(-c3cc(OCC4CCO4)ccc3F)c12)[C@@H]1C[C@H](CN2CC[S+]([O-])CC2)C1
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Compound Formula C25H30FN5O3S
Compound Structure
Protein Name
 Protein Info 
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 251 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 200 nM