Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-methoxy-4-{[6-(3,4,5-trifluorophenyl)-[1,2,4]triazolo[4,3-a]pyridazin-3-yl]methoxy}quinoline
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 PubChem ID
CID: 24824705
SID: 49841035
Canonical SMILES
COc1ccc2c(OCc3nnc4ccc(nn34)-c3cc(F)c(F)c(F)c3)ccnc2c1
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Compound Formula C22H14F3N5O2
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001061 PC-2 [Human pancreatic carcinoma China]
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CL000048 PC-3
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM
2 IC50 = 5 nM