Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine
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 PubChem ID
CID: 1229
SID: 14801417
Canonical SMILES
COc1cc(CC(C)N)c(OC)cc1I
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Compound Formula C11H16INO2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 2.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.2 nM
   TI
   LI
   LO
   TS
3
Ki = 1.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.2 nM
2 IC50 = 4 nM
3 Ki = 2 nM
4 Ki = 42.7 nM