Brief Information of the Compound and Protein
Compound Name
 Compound Info 
EPZ005030
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 PubChem ID
CID: 60160559
Canonical SMILES
CC(C)n1ncc2c(cc(nc12)-c1ccc(CN2CCOCC2)cc1)C(=O)NCc1c(C)cc(C)[nH]c1=O
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Compound Formula C29H34N6O3
Compound Structure
Protein Name
 Protein Info 
Histone-lysine N-methyltransferase EZH2
Protein Classification
Epigenetic regulator
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Writer
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Protein methyltransferase
Uniprot ID
Q15910
Gene Name
EZH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000175 G-401
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 10500 nM
   TI
   LI
   LO
   TS
CL000346 L-5178-Y
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 400 nM
2 Ki = 180 nM