Brief Information of the Compound and Protein
Compound Name
2-[4-[3-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-2-hydroxypropyl]piperazin-1-yl]benzonitrile
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PubChem ID
CID: 127028473
Canonical SMILES
CC1(NC(=O)N(CC(O)CN2CCN(CC2)c2ccccc2C#N)C1=O)c1ccc(F)cc1
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Compound Formula C24H26FN5O3
Compound Structure
Protein Name
5-hydroxytryptamine receptor 7
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P34969
Gene Name
HTR7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 343 nM
   TI
   LI
   LO
   TS
2
Ki = 14 nM
   TI
   LI
   LO
   TS