Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(2-aminothiazol-4-yl)-N-(4-(((2S,5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)acetamide
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 PubChem ID
CID: 44472590
SID: 85752514
Canonical SMILES
Nc1nc(CC(=O)Nc2ccc(C[C@@H]3CC[C@@H](N3)[C@H](O)c3ccccc3)cc2)cs1
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Compound Formula C23H26N4O2S
Compound Structure
Protein Name
 Protein Info 
Beta-3 adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P13945
Gene Name
ADRB3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 0.9 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.98 nM
   TI
   LI
   LO
   TS