Brief Information of the Compound and Protein
Compound Name
3-amino-5-[(2S)-3-methylbutan-2-yl]-7-(1-methyl-5-morpholin-4-ylpyrazol-3-yl)-1H-pyrazolo[4,3-c]pyridin-4-one
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PubChem ID
CID: 117625437
Canonical SMILES
CC(C)[C@H](C)n1cc(-c2cc(N3CCOCC3)n(C)n2)c2[nH]nc(N)c2c1=O
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Compound Formula C19H27N7O2
Compound Structure
Protein Name
Non-receptor tyrosine-protein kinase TYK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P29597
Gene Name
TYK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.55 nM