Brief Information of the Compound and Protein
Compound Name
2-[4-[(3,4-difluorophenyl)methyl]piperazin-1-yl]-5,7-dimethoxychromen-4-one
    Show/Hide
PubChem ID
CID: 127042920
Canonical SMILES
COc1cc(OC)c2c(c1)oc(cc2=O)N1CCN(Cc2ccc(F)c(F)c2)CC1
    Show/Hide
Compound Formula C22H22F2N2O4
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000781 MCF7/Topo Homo sapiens (Human)  1
1
IC50 = 66600 nM
   TI
   LI
   LO
   TS