Brief Information of the Compound and Protein
Compound Name
5-[6-amino-5-(4-chlorophenyl)pyridin-3-yl]-1H-pyridin-2-one
    Show/Hide
PubChem ID
CID: 127026999
Canonical SMILES
Nc1ncc(cc1-c1ccc(Cl)cc1)-c1ccc(=O)[nH]c1
    Show/Hide
Compound Formula C16H12ClN3O
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase MSN subfamily
Uniprot ID
O95819
Gene Name
MAP4K4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000362 GripTite 293 MSR Homo sapiens (Human)  1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 96 nM