Brief Information of the Compound and Protein
Compound Name
5-[6-amino-5-(4-chlorophenyl)pyridin-3-yl]pyrimidin-2-amine
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PubChem ID
CID: 127036775
Canonical SMILES
Nc1ncc(cn1)-c1cnc(N)c(c1)-c1ccc(Cl)cc1
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Compound Formula C15H12ClN5
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase MSN subfamily
Uniprot ID
O95819
Gene Name
MAP4K4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000362 GripTite 293 MSR Homo sapiens (Human)  1
1
IC50 = 470 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14.9 nM