Brief Information of the Compound and Protein
Compound Name
7-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
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PubChem ID
CID: 11846300
SID: 17159067
Canonical SMILES
CN1CCN(CC1)C1=Nc2ccc(Cl)cc2Oc2ccccc12
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Compound Formula C18H18ClN3O
Compound Structure
Protein Name
Histamine H1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
EC50 = 6.761 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 8.318 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 7.762 nM