Brief Information of the Compound and Protein
| Compound Name |
3-(2-phenylethynyl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Proto-oncogene tyrosine-protein kinase receptor Ret
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Protein Classification |
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Ret family
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| Uniprot ID | Gene Name | RET |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | IC50 = 8 nM | ||
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| 2 | IC50 = 14 nM | ||
| 3 | IC50 = 54 nM | ||
| 4 | IC50 = 56.5 nM | ||
| 5 | IC50 = 57 nM | ||
| 6 | IC50 = 75 nM | ||
| 7 | IC50 = 2650 nM | ||
| 8 | IC50 = 3130 nM | ||