Brief Information of the Compound and Protein
Compound Name
 Compound Info 
IBRUTINIB
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 PubChem ID
CID: 24821094
SID: 49837088
Canonical SMILES
Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)[C@@H]1CCCN(C1)C(=O)C=C
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Compound Formula C25H24N6O2
Compound Structure
Protein Name
 Protein Info 
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
GI50 = 120 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 73 nM
2 IC50 > 1000 nM