Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(-)-3-(1-Propyl-piperidin-3-yl)-phenol
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 PubChem ID
CID: 5311189
SID: 14822655
Canonical SMILES
CCCN1CCC[C@H](C1)c1cccc(O)c1
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Compound Formula C14H21NO
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 163 nM
   TI
   LI
   LO
   TS
2
EC50 = 376 nM
   TI
   LI
   LO
   TS
3
EC50 = 844 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 8.5 nM
   TI
   LI
   LO
   TS
2
Ki = 39 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 17.4 nM
   TI
   LI
   LO
   TS
2
Ki = 2268 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 9 nM
2 Ki = 27 nM
3 Ki = 137 nM