Brief Information of the Compound and Protein
Compound Name
5-(2,3-difluorophenyl)-N-[[1-(2-methoxyethyl)piperidin-4-yl]methyl]-1H-indazole-3-carboxamide
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PubChem ID
CID: 71680628
Canonical SMILES
COCCN1CCC(CNC(=O)c2n[nH]c3ccc(cc23)-c2cccc(F)c2F)CC1
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Compound Formula C23H26F2N4O2
Compound Structure
Protein Name
Glycogen synthase kinase-3 beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase GSK family
Uniprot ID
P49841
Gene Name
GSK3B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 18 nM
2 Ki = 15 nM