Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Trans-2-Chloro-N-[4-(3-methyl-2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-cyclohexyl]-5-trifluoromethyl-benzamide
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 PubChem ID
SID: 125006128
Canonical SMILES
Cn1c(=O)n(C[C@H]2CC[C@H](NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)c2ccccc21
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Compound Formula C23H23ClF3N3O2
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 37 nM
   TI
   LI
   LO
   TS