Brief Information of the Compound and Protein
Compound Name
 Compound Info 
Trans-2-chloro-N-{-4-((5'-fluoro-2'-oxospiro[cyclopropane-1,3'-indoline]-1'-yl)methyl)cyclohexyl}-5-(trifluoromethyl)benzamid
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 PubChem ID
SID: 125006449
Canonical SMILES
O=C(N[C@H]1CC[C@H](CN2C(=O)C3(CC3)c3cc(F)ccc32)CC1)c1cc(C(F)(F)F)ccc1Cl
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Compound Formula C25H23ClF4N2O2
Compound Structure
Protein Name
 Protein Info 
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 9 nM
   TI
   LI
   LO
   TS