Brief Information of the Compound and Protein
Compound Name
N-(5-Methyl-pyrazin-2-ylmethyl)-3-(5-methyl-pyridin-2-yl)-5-(5-oxo-6-oxa-4-aza-spiro[2.4]hept-4-yl)-benzamide
    Show/Hide
PubChem ID
CID: 49847450
SID: 104175694
Canonical SMILES
Cc1ccc(-c2cc(C(=O)NCc3cnc(C)cn3)cc(N3C(=O)OCC34CC4)c2)nc1
    Show/Hide
Compound Formula C24H23N5O3
Compound Structure
Protein Name
P2X purinoceptor 3
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Uniprot ID
P49654
Gene Name
P2RX3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 4.365 nM
   TI
   LI
   LO
   TS