Brief Information of the Compound and Protein
Compound Name
2-Methylsulfanyl-3-phenylsulfonyl-5,6,7,8-tetrahydro-pyrazolo[5,1-b]quinazoline
    Show/Hide
PubChem ID
CID: 46884709
Canonical SMILES
CSc1nn2cc3CCCCc3nc2c1S(=O)(=O)c1ccccc1
    Show/Hide
Compound Formula C17H17N3O2S2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 98.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 479 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
Ki = 7.97 nM
   TI
   LI
   LO
   TS