Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9012461, 12
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 PubChem ID
CID: 68282490
Canonical SMILES
CC(C(N)=O)c1ccccc1CCc1nc(Nc2ccc(cc2)C2CCNCC2)ncc1C(F)(F)F
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Compound Formula C27H30F3N5O
Compound Structure
Protein Name
 Protein Info 
Focal adhesion kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Fak family
Uniprot ID
Q05397
Gene Name
PTK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 81 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12 nM
2 Kd = 0.92 nM