Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8921559, 52
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Canonical SMILES
NC(=O)C(N[C@H]1CC[C@@H](CC1)C1CNc2ccccc12)C1CCN(CC1)C(=O)\C=C\c1cc(F)c(F)c(F)c1
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Compound Formula C30H35F3N4O2
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 950 nM
   TI
   LI
   LO
   TS