Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(2R)-1-[(4S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-hydroxy-3-methylbutanamide
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 PubChem ID
CID: 57889181
Canonical SMILES
CC(C)[C@@H](NC(=O)CC(C)(C)O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1
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Compound Formula C23H35ClN2O4
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P32246
Gene Name
CCR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
2
Ki = 3.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.2 nM