Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(benzenesulfonyl)-N,5,7-trimethylpyrazolo[1,5-a]pyrimidin-2-amine
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 PubChem ID
CID: 44516817
SID: 85851631
Canonical SMILES
CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccccc1
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Compound Formula C15H16N4O2S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
2
Ki = 0.257 nM
   TI
   LI
   LO
   TS
3
Ki = 0.26 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.2 nM