Brief Information of the Compound and Protein
Compound Name
2-[[1-(3,3-difluorocyclopentyl)-5-[1-(oxetan-3-yl)piperidin-4-yl]pyrazol-3-yl]amino]pyridine-4-carbonitrile
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PubChem ID
CID: 122193946
Canonical SMILES
FC1(F)CCC(C1)n1nc(Nc2cc(ccn2)C#N)cc1C1CCN(CC1)C1COC1
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Compound Formula C22H26F2N6O
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 12
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
Uniprot ID
Q12852
Gene Name
MAP3K12
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 721 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 48 nM