Brief Information of the Compound and Protein
Compound Name
2-[[4-cyclopropyl-5-[1-(oxetan-3-yl)piperidin-4-yl]-1,3-thiazol-2-yl]amino]pyridine-4-carbonitrile
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PubChem ID
CID: 122194091
Canonical SMILES
N#Cc1ccnc(Nc2nc(C3CC3)c(s2)C2CCN(CC2)C2COC2)c1
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Compound Formula C20H23N5OS
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 12
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
Uniprot ID
Q12852
Gene Name
MAP3K12
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 8600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 569 nM