Brief Information of the Compound and Protein
Compound Name
4'-fluoro-5'-[5-methoxy-4-oxo-3-(2-phenylpyrazol-3-yl)pyridazin-1-yl]-1'-methylspiro[cyclobutane-1,3'-indole]-2'-one
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PubChem ID
CID: 68014634
Canonical SMILES
COc1cn(nc(-c2ccnn2-c2ccccc2)c1=O)-c1ccc2N(C)C(=O)C3(CCC3)c2c1F
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Compound Formula C26H22FN5O3
Compound Structure
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Protein Classification
Enzyme
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Phosphodiesterase
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Phosphodiesterase 10
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Phosphodiesterase 10A
Uniprot ID
Q9Y233
Gene Name
PDE10A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 0.13 nM
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