Brief Information of the Compound and Protein
Compound Name
(4R)-4-[(1R)-1-[[6-(1-methylpyrazol-4-yl)-[1,2]thiazolo[4,3-c]pyridin-4-yl]oxy]ethyl]pyrrolidin-2-one
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PubChem ID
CID: 122191643
Canonical SMILES
C[C@@H](Oc1nc(cc2nscc12)-c1cnn(C)c1)[C@H]1CNC(=O)C1
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Compound Formula C16H17N5O2S
Compound Structure
Protein Name
Tyrosine-protein kinase SYK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Syk family
Uniprot ID
P43405
Gene Name
SYK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
IC50 = 247 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM