Brief Information of the Compound and Protein
Compound Name
N-propyl-5-[3-[2-(trifluoromethyl)phenyl]pyridin-4-yl]-1,3-thiazol-2-amine
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PubChem ID
CID: 117918855
Canonical SMILES
CCCNc1ncc(s1)-c1ccncc1-c1ccccc1C(F)(F)F
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Compound Formula C18H16F3N3S
Compound Structure
Protein Name
LIM domain kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LISK family
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TKL protein kinase LIMK subfamily
Uniprot ID
P53667
Gene Name
LIMK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 37 nM
   TI
   LI
   LO
   TS
CL000142 ZR-75-1 Homo sapiens (Human)  1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS