Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methoxyethyl N-[11-(dicyclopropylcarbamoyl)-10-ethyl-3-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-7-yl]carbamate
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 PubChem ID
CID: 122191619
Canonical SMILES
CCn1c(cc2c1nc(NC(=O)OCCOC)c1ncn(C)c21)C(=O)N(C1CC1)C1CC1
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Compound Formula C22H28N6O4
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 25 nM