Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N,N-dicyclopropyl-10-[(2S)-2,3-dihydroxypropyl]-3-methyl-7-(methylamino)-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene-11-carboxamide
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 PubChem ID
CID: 91827515
Canonical SMILES
CNc1nc2n(C[C@H](O)CO)c(cc2c2n(C)cnc12)C(=O)N(C1CC1)C1CC1
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Compound Formula C20H26N6O3
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000224 SET-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 720 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8.2 nM