Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-aminopentanedioic acid
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 PubChem ID
CID: 33032
SID: 15297417
Canonical SMILES
N[C@@H](CCC(O)=O)C(O)=O
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Compound Formula C5H9NO4
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000051 BHK-21
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  1
1
Ki = 11000 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 12589.25 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 1800 nM
   TI
   LI
   LO
   TS
2
Ki = 1819.7 nM
   TI
   LI
   LO
   TS
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  4
1
EC50 = 1767 nM
   TI
   LI
   LO
   TS
2
EC50 = 1827 nM
   TI
   LI
   LO
   TS
3
EC50 = 2351 nM
   TI
   LI
   LO
   TS
4
EC50 = 2575 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 290 nM
2 EC50 = 4700 nM
3 Ki = 1200 nM