Brief Information of the Compound and Protein
Compound Name
5-[4-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
    Show/Hide
PubChem ID
CID: 122189391
Canonical SMILES
COc1ccccc1N1CCN(CCc2cn(nn2)-c2ccn3ncc(C=O)c3c2)CC1
    Show/Hide
Compound Formula C23H25N7O2
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
Ki = 9.4 nM
   TI
   LI
   LO
   TS
2
Ki = 18 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 549.54 nM
   TI
   LI
   LO
   TS
2
EC50 = 4365.16 nM
   TI
   LI
   LO
   TS