Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyrrolylcarboxamido)propanoyl]tetrahydro-1H-2-pyrrolecarboxamide
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 PubChem ID
CID: 638678
SID: 16136709
Canonical SMILES
NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1
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Compound Formula C16H22N6O4
Compound Structure
Protein Name
 Protein Info 
Thyrotropin-releasing hormone receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide receptor
Uniprot ID
P21761
Gene Name
TRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 1 nM
   TI
   LI
   LO
   TS
2
EC50 = 3.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 2.6 nM
   TI
   LI
   LO
   TS
4
IC50 = 26 nM
   TI
   LI
   LO
   TS