Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R)-2-(4-carboxybenzylcarbamoyl)-1-(2-phenoxyethyl)piperidinium chloride
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 PubChem ID
CID: 89914843
Canonical SMILES
Cl.O=C(O)c1ccc(CNC(=O)[C@H]2CCCCN2CCOc2ccccc2)cc1
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Compound Formula C22H27ClN2O4
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E2 receptor EP4 subtype
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P35408
Gene Name
PTGER4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 18.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 203 nM
   TI
   LI
   LO
   TS
3
Ki = 126 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 899 nM