Brief Information of the Compound and Protein
Compound Name
5-(2-chloro-4-(thiazol-5-yl)phenyl)-3-ethyl-2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4(3H)-one
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PubChem ID
CID: 122183174
Canonical SMILES
CCn1c(Nc2ccc(N3CCN(C)CC3)cc2)ncc(-c2ccc(-c3cncs3)cc2Cl)c1=O
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Compound Formula C26H27ClN6OS
Compound Structure
Protein Name
Serine/threonine-protein kinase PAK 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase PAKA subfamily
Uniprot ID
Q13153
Gene Name
PAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000243 MCF-10A Homo sapiens (Human)  1
1
IC50 = 88 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.8 nM